2-Phenethylamines in Medicinal Chemistry: A Review.

Carlos T Nieto,Alejandro Manchado,Leland Belda,David Diez,Narciso M Garrido

Molecules (Basel, Switzerland)（2023）

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摘要

A concise review covering updated presence and role of 2-phenethylamines in medicinal chemistry is presented. Open-chain, flexible alicyclic amine derivatives of this motif are enumerated in key therapeutic targets, listing medicinal chemistry hits and appealing screening compounds. Latest reports in discovering new bioactive 2-phenethylamines by research groups are covered too.

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关键词

2-phenethylamine,5-HT,DAT,MAO,PPAR,TAAR1,adrenoceptors,carbonyl anhydrase,dopamine receptor,ligands,medicinal chemistry,sigma receptors

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