TRIM10 Is Downregulated in Acute Myeloid Leukemia and Plays a Tumor Suppressive Role via Regulating NF-κB Pathway.

Lin Li, Qi Li,Zhengrong Zou,Zoufang Huang,Yijian Chen

Cancers（2023）

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摘要

Our results strongly suggested that TRIM10 plays a tumor suppressive role in AML development associated with the NF-κB signal pathway and may be a potential target of epigenetic therapy against leukemia.

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关键词

NF-κB,TRIM10,acute myeloid leukemia,epigenetic regulation,tumor suppressive

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