Astragalus polysaccharide prevents heart failure-induced cachexia by alleviating excessive adipose expenditure in white and brown adipose tissue.

Dufang Ma,Tao Wu,Yiwei Qu,Jinlong Yang,Lu Cai,Xiao Li,Yong Wang

Lipids in health and disease（2023）

Cited 1|Views10

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Abstract

APS prevented lipolysis and adipose browning in WAT and decreased BAT thermogenesis. These effects may be related to suppressed sympathetic activity and inflammation. This study provides a potential approach to treat HF-induced cardiac cachexia.

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Key words

Adipose expenditure,Astragalus polysaccharide,Brown adipose tissue,Cardiac cachexia,White adipose tissue

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