Differential effect of dementia etiology on cortical stiffness as assessed by MR elastography.
NeuroImage. Clinical(2023)
摘要
Both tissue-confined and regionally-aware stiffness estimates exhibited unique and complementary stiffness differences in various etiologies of dementia. Our results suggest that mechanical alterations measured by MRE reflect both tissue-specific differences as well as environmental effects. Multi-inversion schemes in MRE may provide new insights into the relationships between neuropathology and brain biomechanics.
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关键词
Alzheimer’s,Brain stiffness,Dementia,Dementia with Lewy bodies,Frontotemporal dementia,Inversion,Magnetic resonance elastography (MRE),Neural network,Neurodegeneration
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