Adaptive Evolutionary Strategy Coupled with an Optimized Biosynthesis Process for the Efficient Production of Pyrroloquinoline Quinone from Methanol

Yang Ren,Xinwei Yang, Lingtao Ding, Dongfang Liu,Yong Tao,Jianzhong Huang,Chongrong Ke

BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS（2023）

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Pyrroloquinoline quinone,Adaptive laboratory evolution (ALE),Hyphomicrobium denitrificans,Response surface methodology (RSM),Two-stage pH control strategy

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