Long Non-Coding RNA TUG1 Attenuates Insulin Resistance in Mice with Gestational Diabetes Mellitus via Regulation of the MicroRNA-328-3p/SREBP-2/ERK Axis.

Xuwen Tang,Qingxin Qin,Wenjing Xu,Xuezhen Zhang

Diabetes & metabolism journal（2023）

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摘要

Our study provides evidence that the lncRNA TUG1 may prevent IR following GDM through competitively binding to miR-328-3p and promoting the SREBP-2-mediated ERK signaling pathway inactivation.

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关键词

Diabetes, gestational,Extracellular signal-regulated MAP kinases,Insulin resistance,MicroRNAs,RNA, long noncoding,Sterol regulatory element binding protein 2

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