A Retrospective, Nested Case-Control Study to Develop a Biomarker-Based Model for ARDS Diagnostics.
Clinical laboratory(2023)
摘要
A combination of biomarkers could enhance ARDS diagnostics, which has obvious ramifications for patient care and prognosis. It may be possible to develop a predictive ARDS nomogram; however, of the combinations tested here, we tentatively recommend PaO2/FiO2 + CRP + Ang-2 + CC16 + HMGB1. This is because of the cost implications in contrast with benefit involved in utilizing the more elaborate model. Further health economics research is required to consider the opportunity cost for emergency care policy.
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关键词
acute respiratory distress syndrome,biomarkers,club cell protein 16,angiopoietin 2,soluble receptor for advanced glycation end-products,high-mobility group box 1 protein,surfactant protein D,intensive care unit
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