Sex and prior exposure jointly shape innate immune responses to a live herpesvirus vaccine.

Foo Cheung,Richard Apps,Lesia Dropulic,Yuri Kotliarov,Jinguo Chen,Tristan Jordan,Marc Langweiler,Julian Candia,Angelique Biancotto,Kyu Lee Han,Nicholas Rachmaninoff,Harlan Pietz,Kening Wang,John S Tsang,Jeffrey I Cohen

eLife（2023）

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摘要

Intramural Research Program of the NIH, the National Institute of Allergy and Infectious Diseases, and other institutes supporting the Trans-NIH Center for Human Immunology, Autoimmunity, and Inflammation. The vaccine trial was supported through a clinical trial agreement between the National Institute of Allergy and Infectious Diseases and Sanofi Pasteur. Clinical trial number: NCT01915212.

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关键词

herpes simplex,human,infectious disease,innate immunity,medicine,microbiology,sex dimorphism,systems immunology,transcriptomics,vaccine

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