Phase-and disorder-specific differences in peripheral metabolites of the kynurenine pathway in major depression, bipolar affective disorder and schizophrenia.

Murielle Brum,Matthias Nieberler,Christopher Kehrwald,Katrin Knopf,Nathalie Brunkhorst-Kanaan,Semra Etyemez,Kelly A Allers,Robert A Bittner,David A Slattery,Rhiannon V McNeill,Andreas Reif,Sarah Kittel-Schneider

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry（2023）

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摘要

Our data suggests an involvement of the kynurenine pathway in mental disorders, especially BD but disqualifying those metabolites as biomarkers for differential diagnosis.

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关键词

Kynurenine,biomarker,inflammation,mental disorders,tryptophan

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