Methylation changes induced by a glycodendropeptide immunotherapy and associated to tolerance in mice.

Rafael Núñez,María J Rodríguez,Clara Lebrón-Martín,María Del Carmen Martín-Astorga,Francisca Palomares,Javier Ramos-Soriano,Javier Rojo, María J Torres,José Antonio Cañas, Cristobalina Mayorga

Frontiers in immunology（2022）

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摘要

In conclusion, different doses of D1ManPrup3-SLIT induce different DNA methylation changes, which are reflected in the induction of distinct responses, tolerance, or desensitization.

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关键词

dendritic cells,epigenetic changes,immunomodulation,lipid transfer proteins,sublingual immunotherapy

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