A systematic review of trials currently investigating therapeutic modalities for post-acute COVID-19 syndrome and registered on WHO International Clinical Trials Platform.

Nader A Fawzy,Bader Abou Shaar,Rand M Taha,Tarek Z Arabi,Belal N Sabbah,Mohamad S Alkodaymi,Osama A Omrani,Tariq Makhzoum,Najwa E Almahfoudh, Qasem A Al-Hammad,Wed Hejazi,Yasin Obeidat,Naden Osman,Khaled M Al-Kattan,Elie F Berbari,Imad M Tleyjeh

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases（2023）

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摘要

We identified 388 registered trials, with a high degree of heterogeneity, exploring 144 unique mono-therapeutic interventions for PACS. Most studies target general alleviation of symptoms. There is a need for further high-quality and methodologically robust PACS treatment trials to be conducted with standardization of outcomes while following WHO's recommendation for uniform evaluation and treatment.

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关键词

COVID-19,Coronavirus,Long COVID,Post-acute COVID-19 syndrome,SARS-CoV-2

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