The dynamic cellular landscape of grafts with acute rejection after heart transplantation.

Deqiang Kong,Siyuan Huang,Xiaolong Miao,Jiaxin Li,Zelai Wu,Yang Shi, Han Liu,Yuancong Jiang,Xing Yu,Mengyao Xie,Zhonghua Shen,Jinzhen Cai,Ruibin Xi,Weihua Gong

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation（2023）

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摘要

The findings of our study unveiled a novel CFB subcluster that might mediate acute cardiac rejection. Targeting CXCR3 could prolong allograft survival.

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CXCR3,acute cellular rejection,fibroblasts,heart transplantation,scRNA-seq

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