Cellular Uptake and Transport Mechanism of 6-Mercaptopurine Nanomedicines for Enhanced Oral Bioavailability.

Yaru Zou,Wei Gao, Huizhen Jin,Chenmei Mao,Yi Zhang,Xiaoling Wang,Dong Mei,Libo Zhao

International journal of nanomedicine（2023）

引用 2|浏览17

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摘要

6-MPNs improve the oral bioavailability through multiple pathways, including active transport, paracellular transport, lymphatic delivery and MRP4 transporter. The findings of current study may shed light on the cellular uptake and transcellular trafficking mechanism of oral nanomedicines.

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关键词

cellular uptake,nanomedicines,oral bioavailability,transport mechanism

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