Impact of surface coating and systemic anticoagulants on hemostasis and inflammation in a human whole blood model.

Doreen Tabea Spiegelburg,Marco Mannes,Anke Schultze,Frieder Scheibenberger, Frederik Müller,Amadeo Klitzing,David Alexander Christian Messerer,Kristina Nilsson Ekdahl,Bo Nilsson,Markus Huber-Lang,Christian Karl Braun

PloS one（2023）

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摘要

The MPC-based protocols demonstrated better hemocompatibility compared to CHC, and ENOX and FPX proved useful for additional anticoagulation. Furthermore, this simple-to-use whole blood model may be useful for experimental analyses of the early coagulatory and immunological response without decalcification.

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关键词

systemic anticoagulants,hemostasis,surface coating,blood

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