The role of oxidative stress in genome destabilization and adaptive evolution of bacteria
Gene(2023)
摘要
•Suboptimal, novel and toxic substrates induce oxidative stress in bacteria.•Stress regulons under the influence of ROS destabilize the bacterial genome.•ROS-induced mutagenesis and HGT accelerate evolution under selective pressure.•To accelerate bacterial evolution, the average mutagenesis level is favorable (∼10−8).
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关键词
Oxidative stress,Genome destabilization,Adaptation,Bacteria,Organic pollutants
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