炎症性肠病消化道肿瘤的发生风险与监测
Chinese Journal of Inflammatory Bowel Diseases(2022)
Abstract
炎症性肠病(IBD)是一组病因不明的肠道慢性非特异性炎性疾病。IBD的慢性炎症状态累及整个胃肠道,其发生结直肠癌和小肠癌等消化道肿瘤的风险明显增加,严重影响预后。随着我国IBD的患病率逐渐升高,IBD相关消化道肿瘤的防治仍然是临床医生面临的重大挑战。对IBD患者消化道肿瘤的发生风险进行危险分层从而制定个体化监测策略具有重要意义。生物标志物的开发、内镜方法和活检方式的选择均是未来研究的方向。本文就IBD消化道肿瘤的流行病学、危险因素、生物标志物和内镜监测作一论述。
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Key words
Gastrointestinal tumors,Inflammatory bowel disease,Colorectal cancer,Surveillance,Risk factors
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