The pathogenic role of lupus-specific autoantibodies and Interleukin-6 on demyelination of the brainstem and spinal cord in systemic lupus erythematosus.
Lupus(2023)
Abstract
CSF IL-6 could be a surrogating marker for disease activity, and serum anti-Smith antibody permeabilizes the BBB in patients with NPSLE, supporting the development of NMOSD-like CNS lesions.
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Key words
Systemic lupus erythematosus,autoantibody,cerebrospinal fluid,interleukin-6,neuromyelitis optica spectrum disorder
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