LncRNA BCAR4 promotes migration, invasion, and chemo-resistance by inhibiting miR-644a in breast cancer.

Tangwei Wu,Xiaoyi Li,Ge Yan,Zheqiong Tan,Dan Zhao,Shuiyi Liu,Hui Wang,Yuan Xiang,Weiqun Chen,Hongda Lu,Xinghua Liao,Yong Li,Zhongxin Lu

Journal of experimental & clinical cancer research : CR（2023）

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摘要

Our findings provide insights into the oncogenic role of BCAR4 and implicate BCAR4 as a potential diagnostic biomarker and a promising therapeutic agent to suppress metastasis and inhibit chemo-resistance of breast cancer.

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关键词

Breast cancer,Chemo-resistance,Invasion,Migration,ncRNA

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