Refractive index tomography for drug-induced liver injury analysis

Juan M. Soto,Fabio A. Aguilar Mora,Jose A. Rodrigo,Yana Geng,Nshunge Musheshe,Manon Buist-Homan,Frank Lezoualc'h,Xiaodong Cheng,Martina Schmidt,Han Moshage,Tatiana Alieva

ADVANCES IN MICROSCOPIC IMAGING III（2021）

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Abstract

Refractive index tomography compatible with conventional microscope is used for analyzing primary rat hepatocytes injury induced by pharmacological treatments. We found that mitochondria malfunctioning is correlated with refractive index variations.

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