Sulfasalazine for the treatment of preeclampsia in a nitric oxide synthase antagonist mouse model

Natalie K. Binder,Natasha de Alwis,Sally Beard,Elif Kadife,Alesia Harper,Tu'uhevaha J. Kaitu'u-Lino,Fiona C. Brownfoot,Natalie J. Hannan

Placenta（2023）

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摘要

•Sulfasalazine modestly decreases blood pressure in a mouse model of preeclampsia.•Sulfasalazine was unable to rescue fetal growth restriction.•Sulfasalazine may improve vasoactivity.

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关键词

Preeclampsia,Sulfasalazine,Fetal growth restriction,Hypertension,Vasoactivity

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