Atypical presentation of covid-19 in an adolescent renal transplant recipient

Tamara Jaye,Nonhlanhla Mbenenge, Selwyn Schwartz,Jennifer Geel, Jason Parry, Daniella Marques, Beauty Sangweni,Tholang Khumalo,Cecil Levy

CURRENT ALLERGY & CLINICAL IMMUNOLOGY(2021)

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Abstract
Towards the end of 2019, a new coronavirus (CoV) was described emerging from Wuhan, China. Given its phylogenetic similarity to SARS-CoV, the new coronavirus was named severe-acute respiratory syndrome virus-2 and the disease it caused was named coronavirus disease of 2019 (COVID-19). There are few reports of paediatric renal transplant recipients infected with SARS-CoV-2 and, although guidelines for the management of solid-organ transplant recipients exposed to SAR-CoV-2 have been published, there are few paediatric-specific guidelines. We present a case of an unusual presentation of COVID-19 in an adolescent transplant recipient who presented with transient facial angioedema and a non-specific skin rash. She developed acute kidney injury, which resolved without any intervention. We suggest that, in future, an international registry of paediatric transplant recipients infected with COVID-19 be established to delineate more clearly the presenting features, clinical course and challenges encountered in treating these patients.
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Key words
COVID-19,Coronavirus,SARS-CoV-2,kidney transplant,children,adolescent,angioedema,skin rash,arthralgia,acute kidney injury
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