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Gene regulators associating the T2DM and periodontitis contributing disease prognostic markers and therapeutic target

Chanchal Katariya, G. Kaarthikeyan, Paramasivam,Mrim M. Alnfiai,Ahmed Alamoudi,Maha A Bahammam,Ammar Almarghlani,Talal M Zahid,Khalid J. Alzahrani,Hamsa Jameel Banjer,Fuad M. Alzahrani,Mohammad Assaggaf,Hosam Ali Baeshen,Mazen F. Alkahtany,Shankargouda Patil

Journal of King Saud University: Science（2023）

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Abstract
Periodontitis can be exacerbated by variety of systemic disorders including type 2 diabetes. T2DM patients exhibited a threefold increased risk of periodontitis. The mechanism through which T2DM induces periodontitis is uncertain. This study aims to identify co-regulatory molecules involved in T2DM periodontitis. Understanding the mechanisms could lead to new prognostic biomarkers and therapeutic targets.
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Key words
Biomarkers,Diabetes Mellitus,Gene Expression,Periodontitis,Prognosis
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