P53 Pharmacological diabetes approach in patients with solid organ transplantation

Background: Diabetes mellitus (DM) is a complication of solid organ transplantation and generally treated with insulin, recently new therapies have been implemented with good results. Objetive: We describe and evaluate pharmacological diabetes therapy in patients undergoing solid organ transplantation, as well as its impact on glucometabolic control. Method: This is an observational, retrospective study. We include solid organ transplantation patients with a post-transplant DM or pre-transplant DM diagnosis, who attended to a medical consultation between 7/2015 and 8/2019. Patients with less than 2 medical consultation in a period of 2 years were excluded. HbA1c levels and estimated glomerular filtration rate (eGFR) using the CKD-EPI equation were evaluated. The rate of change of immunosuppressive therapy and pharmacological diabetes therapy at 3, 6, 12, 18 and 24 months of follow-up was described. Statistical method: qualitative variables are described in absolute frequency / percentage and the quantitative variables in median / range according to their distribution. Nonparametric tests and Fisher's test were used to analyze differences.