EPIDEMIOLOGICAL MANIFESTATIONS OF PREVALENCE OF GLOMERULAR-TUBULOINTERSTITIAL DISEASES OF KIDNEYS AND URETER IN AREAS WITH DIFFERENT LEVELS OF ANTHROPOGENIC LOAD

The article reviews the features of the manifestations of the prevalence of glomerular-tubulointerstitial diseases of kidneys and ureter (GTIDKU) in Ufa, Salavat and Sterlitamak with severe anthropogenic load in comparison with the more prosperous Octyabrskiy. Epidemiological manifestations of GTIDKU were evaluated in children, adolescents, adults and the whole population by average long-term indices in dynamics and some periods of observation. Research results revealed significant differences in the prevalence of manifestations of GTIDKU both between the same groups studied on the analyzed areas and between different cohorts on each of them. Among the studied areas the most unfavorable in relation to the intensity of the prevalence of GTIGKU were not only the most favorable in relation to anthropogenic loads Среди изучаемых территорий наименьшее неблагополучие по выраженности превалентности Octyabrskiy, but also in the less burdened Salavat while maximum value of general prevalence of GTIGKU in ecologically unfavorable Ufa. Possible connection of observed manifestations with character of qualitative contents of the environment pollutants in Ufa in comparison with Sterlitamak and Salavat and also necessity of increase of the effectiveness of epidemiological diagnostics of GTIGKU in Sterlitamak, Salavat and Octyabrskiy under generally accepted standards are discussed. At that the attention is paid to the expediency of the organization of epidemiological case-control research for the revealing of groups with the highest risk of development of GTIGKU including chronic pyelonephritis. Specification of these statements will allow to optimize measures of the effective management of this pathology on different levels of providing medical aid for such patients.