Correlation of Serum Magnesium and Blood Lipid Profile in Under-Peritoneal Dialysis and Hemodialysis Patients

Background: Lipid abnormalities, is one of the major causes of cardiovascular diseases in under-dialysis patients. This study aimed to assess the relationship of serum magnesium and blood lipid profile in patients under the peritoneal dialysis and hemodialysis. Methods: This cross- sectional study was performed on 110 under-dialysis patients in Zahedan, Iran. Serum lipids and magnesium levels were measured. Data were analyzed using t and Pearson correlation tests. Findings: The mean age of the patients was 46.1 ± 14.7 years. In under-peritoneal dialysis patients, who were not under the treatment of antilipid agents, the correlation of serum magnesium with triglyceride and very low-density lipoprotein cholesterol (VLDL) was significant (P < 0.05); whereas the correlation of serum magnesium with cholesterol and low-density lipoprotein cholesterol (LDL-C) was significant only in subgroup who were under treatment of antilipid agents (P < 0.05). In under-hemodialysis group, the correlation of serum magnesium with cholesterol, triglyceride and was significant (P < 0.05). Conclusion: This study showed that serum magnesium had correlation with serum lipid profile and could contribute to atherosclerosis and cardiovascular diseases in the patients under the peritoneal dialysis and hemodialysis.