TREATMENT OF TEMPORARY MOLARS WITH PULP NECROSIS USING LESION STERILIZATION AND TISSUE REPAIR-a systematic review

Objectives:The purpose of this review was to evaluate the literature on the use of a paste containing a mix of antibiotics use in the treatment of temporary molars with pulp necrosis using the method of lesion sterilization and tissue repair (LSTR) and to compare the clinical and radiological success rate of a mix of antibiotics consisting of Metronidazole,Ciprofloxacin and Minocycline (3Mix-MP) and another mix in which Minocycline was replaced with Clindamycin (3Mix-MP-R). Materials and method: Articles from the Medline database have been evaluated,searched via Pubmed and using MeSH terms Results: Clinical studies performed on temporary molars with pulp necrosis suggest that this mix of three antibiotics has been shown to be an effective treatment without statistically significant differences between the various preparations used to fill the root canals on temporary molars. Conclusions:To date,clinical trials on the use of a paste containing a mix of antibiotics in the treatment of temporary molars with necrotic pulp are limited,and the techniques for using this paste vary slightly from autor to autor.For this method of treatment to become a viable option,the case selection criteria and the clinical protocol must be continuously redefined and updated in order to obtain the best results.Regarding the results obtained with the two variants of the paste,the statistics shows similar results,but additional studies are needed regarding them and a longer term follow-up period to evaluate the exfoliation of these treated teeth.