Efficiency of Repetitive Topical Corticosteroid Embedded Nasopore Tamponing on Wound Healing After Endoscopic Sinus Surgery

Aim: We aimed to maximize the efficiency of topical steroid use in the sinus cavity by application for an extended duration after endoscopic sinus surgery. We also evaluated the efficiency of repetitive application of a topical steroid through the sinus cavity directly on wound healing and earlier postoperative complications. Method: Thirty-five patients who underwent bilateral endoscopic sinus surgery were included in our study. Upon completion of the surgery, randomly, one side of the middle meatus was packed with NasoPore, embedded with a nasal steroid (budesonide 0.5µg/2ml), plus antibiotic cream, and the other side was packed with NasoPore embedded with only antibiotic cream. All the patients were scheduled for follow-up visits at 1, 2, 4, 8, and 12 weeks after surgery for the assessment of outcome measures. Findings: The mean score of synechia, mucosal edema, and granulation tissue was lower in steroid embedded group than nonembedded one, during the first three months after surgery. However, there were no statistically significant differences between the two groups. The mean score of edema was significantly decreased in steroid embedded group when compared to other group. Conclusion: We believe that the use of a steroid embedded in an absorbable nasal packing after ESS is highly safe and effective in prevention of early postop ESS complications, including synechia and granulation.