Novel anti-inflammatory compound from Prosopis africana

JAMAL MEZOGI,,HAFSAT SHITTU,RUANGELIE EDRADA-EBEL,VERONIQUE SEIDEL,ALEXANDER GRAY,YOUSEF A TAHER,GHAZALLA BENHUSEIN

PhytoChem & BioSub Journal（2017）

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摘要

An active natural flavanone compound: 3,7,3,4-tetrahydroxyflavanone, 3- protocatechuate obtained from the stem barks of Prosopis Africana, tested against inflammation and showed a significant anti-inflammatory activity inhibiting COX-2 and iNOS at concentration of 20mM. The structure was established on the basis of their UV, NMR (1D and 2D) spectra, mass spectrometry and polarimeter.

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