Disrupting the nNOS/NOS1AP interaction in the medial prefrontal cortex impairs social recognition and spatial working memory in mice

Esin Candemir,Nikolai Fattakhov,Aet O. Leary,David A. Slattery,Michael J. Courtney,Andreas Reif,Florian Freudenberg

European Neuropsychopharmacology（2023）

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摘要

•Overexpression NOS1AP or NOS1AP396-503 in the mPFC impair social recognition.•Disrupting the nNOS/NOS1AP interaction limits spatial working memory capacity.•NOS1AP or NOS1AP396-503 overexpression in the mPFC does not affect anxiety.

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关键词

mPFC,NOS1AP,CAPON,nNOS,NOS1,NOS-I

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