The use of medical cannabis concomitantly with immune checkpoint inhibitors in non-small cell lung cancer: A sigh of relief?

•Cannabis might alter tumour's microenvironment and, hence, reduce the immune checkpoint inhibitors efficacy.•We investigate this theory in murine models and real-world data.•We found no determinantal effect of this combination in clinic or laboratory.•This conclusion has a great reassuring impact on our patients having non-small cell lung cancer.