Determination of tryptamine analogs in whole blood by 96-well electromembrane extraction and UHPLC-MS/MS

Maria Schüller, Tao Angell-Petersen McQuade,Marianne Skov-Skov Bergh,Stig Pedersen-Bjergaard,Elisabeth Leere Øiestad

Talanta Open（2023）

引用 4|浏览8

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摘要

•For the first time, 96-well electromembrane extraction from whole blood.•Absolute quantification by UHPLC-MS/MS in the lower nM-range.•Validated method for 16 tryptamine analogs according to SWGTOX guidelines.•Excellent greenness score (0.76) from AGREEprep evaluation.

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关键词

Tryptamines,New psychoactive substances (NPS),Electromembrane extraction,UHPLC-MS/MS,Green analytical chemistry

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