Age over 75 does not increase the risk of recurrent venous thromboembolism: Findings from the RIETE registry

Based on current evidence, in most patients with an episode of venous thromboembolism (VTE) extended anticoagulation is generally recommended beyond the initial 3–6 months provided the bleeding risk is acceptably low [1]. Among factors that are expected to increase the risk of (major) bleeding complications is the elderly age. In a recent overview and meta-analysis of 27 prospective cohort and randomized clinical trials, older patients were found to exhibit a higher risk of major or clinically relevant bleeding complications, even with the use of the direct oral anticoagulants (DOAC) [2].