Comparative transcriptomic analysis-based identification of the regulation of foreign proteins with different stabilities expressed in Pichia pastoris .

Tingting Niu, Yi Cui, Xu Shan,Shuzhen Qin,Xuejie Zhou,Rui Wang,Alan Chang, Nan Ma, Jingjing Jing,Jianwei He

Frontiers in microbiology（2022）

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摘要

These findings should shed new light on our understanding of the regulatory mechanism in yeast cells that responds to intracellular folding stress, providing valuable information for the development of a convenient platform that could improve the efficiency of heterologous protein expression in

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关键词

amyloid disease,biofuel,cystatin,pichia pastoris,transcriptomic

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