The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.
Frontiers in molecular neuroscience（2022）
Abstract
Inhibition of PGAM5 expression reduces seizures inhibiting PINK1-mediated mitophagy.
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Key words
PGAM5,PINK1,epilepsy,mitophagy,oxidative stress,seizure
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