HLA-G 3'UTR polymorphism diplotypes and soluble HLA-G plasma levels impact cervical cancer susceptibility and prognosis.

Jun Gan,Xing-Hong Di,Zi-Yi Yan, Yang-Fan Gao,Hui-Hui Xu

Frontiers in immunology（2022）

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摘要

The results of the present study enhance our understanding of how 3'UTR polymorphisms can influence the peripheral sHLA-G plasma level and play a key role in cervical carcinogenesis. This study further confirmed that sHLA-G may represent a novel plasma biomarker for the prognosis and potential therapeutic target of cervical cancer.

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关键词

3’UTR,HLA-G,cervical cancer,diplotypes,sHLA-G

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