Frequent somatic mosaicism in T lymphocyte subsets in individuals with and without multiple sclerosis.
Frontiers in immunology(2022)
Abstract
Somatic variation in T lymphocyte subsets is widespread in both control individuals and MS patients. Somatic mosaicism in T lymphocyte subsets is not enriched in early MS and thus unlikely to contribute to MS risk, but future research needs to address whether a subset of variants influences disease susceptibility.
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Key words
T lymphocytes,human genetics,mosaicism,multiple sclerosis,somatic variants
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