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Specific Binding of the Α-Component of the Lantibiotic Lichenicidin to the Peptidoglycan Precursor Lipid II Predetermines Its Antimicrobial Activity

Irina S. Panina,Sergey V. Balandin,Andrey V. Tsarev,Anton O. Chugunov,Andrey A. Tagaev,Ekaterina I. Finkina,Daria V. Antoshina,Elvira V. Sheremeteva,Alexander S. Paramonov, Jasmin Rickmeyer,Gabriele Bierbaum,Roman G. Efremov,Zakhar O. Shenkarev,Tatiana V. Ovchinnikova

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES（2023）

Cited 11|Views46
Key words
antimicrobial peptides,bacteriocins,Bacillus licheniformis,lantibiotics,lipid II,molecular dynamics,NMR spectroscopy,peptidoglycan,pyrophosphate cage
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