Symptomatic uterine leiomyomatosis with intracaval and intracardiac invasion: Video case report

•Uterine leiomyoma is the most prevalent benign tumor of the female genital tract.•Most patients with uterine leiomyoma are asymptomatic and acute complications are rare.•In the case of intracardiac leiomyomatosis (ICLM), surgery is morbid but highly recommended.•Studies demonstrated that the one-stage procedure is safer from the patient perspective.•Cardiopulmonary bypass reduced the clinical repercussions of surgery and improved the patient's quality of life.