PTPRK, an EGFR Phosphatase, Is Decreased in CeD Biopsies and Intestinal Organoids.

Merlin Nanayakkara,Claudia Bellomo,Francesca Furone,Mariantonia Maglio,Antonella Marano,Giuliana Lania,Monia Porpora,Martina Nicoletti,Salvatore Auricchio,Maria Vittoria Barone

Cells（2022）

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摘要

modulation of PTPRK levels can reduce or increase pEGFR, pERK and proliferation in CeD or CTR organoids, respectively. The CeD organoids can be a good model to study the mechanisms of the disease.

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关键词

EGFR,PTPRK,celiac disease,intestinal organoids

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