Safety and Immunogenicity of a monovalent inactivated influenza A/H5N8 virus vaccine given with and without AS03 or MF59 adjuvants in healthy adults.

Patricia L Winokur,Theresa E Hegmann,Wendy A Keitel,David I Bernstein,Sharon E Frey,Chris Bryant

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

AS03 or MF59-adjuvanted H5N8 IIV generated strong immunogenic responses following two doses. There was poor cross-reactivity for the three antigenically drifted H5N1 strains tested.

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关键词

H5N8,avian influenza,immunogenicity,influenza vaccine,safety

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