Chitosan microspheres loaded with 5Fu and Polydopamine-carbon dots for enhancing chemo-photothermal therapy
Materials Letters(2022)
Abstract
Herein, Carbon dots (CDS) was modified with polydopamine (PDA), and they were encapsulated using chitosan (CS) to prepare dual photosensitizers drug loaded microspheres (CS@CDs-PDA + 5Fu NPs). The microsphere has an average particle size of 255 nm and photothermal conversion efficiency of 69.6 % under 808 nm NIR. Notably, the microsphere showed pH and photothermal response drug release performance, contributing to synergistic chemo-photothermal treatment for tumor cells.
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Key words
Carbon dots,Polydopamine,Photothermal therapy,Drug delivery
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