Furosemide rescues hypercalciuria in familial hypomagnesaemia with hypercalciuria and nephrocalcinosis model.

Natalia Kriuchkova,Tilman Breiderhoff,Dominik Müller,Duygu Elif Yilmaz,Hasan Demirci, Hoora Drewell,Dorothee Günzel,Nina Himmerkus,Markus Bleich,Pontus B Persson,Kerim Mutig

Acta physiologica (Oxford, England)（2023）

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摘要

Furosemide significantly reduces hypercalciuria, likely via upregulation of luminal and basolateral Ca transport systems in the distal nephron and collecting duct in this model for FHHNC.

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关键词

TRPV5,claudin-16,distal calcium reabsorption

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