Emerging strategies and challenges of molecular therapeutics in antileishmanial drug development

Deepak Gupta,Pankaj K Singh,Pavan K Yadav,Tadigoppula Narender,Umesh K Patil,Sanjay K Jain,Manish K Chourasia

International Immunopharmacology（2023）

引用 3|浏览29

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摘要

•Kala-azar is a fatal multiorgan dysfunction with numerous treatment challenges.•Molecular insight into host-parasite interactions is critical for identifying therapeutic targets.•Leishmanial proclivity to evolve into resistant phenotypes necessitates a focus on innovative therapeutic concepts.•Molecular therapeutic approaches offer immense potential in parasite eradication programmes.

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关键词

Molecular therapy,Visceral leishmaniasis,Nanomedicines,Checkpoint targets,Chemotherapy,Molecular therapeutics

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