The Slender Esophagus: Unrecognized Esophageal Narrowing in Eosinophilic Esophagitis
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY(2023)
摘要
INTRODUCTION: Inflammation in eosinophilic esophagitis (EoE) often leads to esophageal strictures. Evaluating esophageal narrowing is clinically challenging. We evaluated esophageal distensibility as related to disease activity, fibrosis, and dysphagia. METHODS: Adult patients with and without EoE underwent endoscopy and distensibility measurements. Histology, distensibility, and symptoms were analyzed. RESULTS: Patients with EoE had significantly lower distensibilities than controls. We found a cohort with esophageal diameter under 15 mm despite lack of dysphagia. DISCUSSION: This study raises concern that current assessments of fibrostenosis are suboptimal. We describe a cohort with unrecognized slender esophagus that were identified through impedance planimetrymeasurements. This tool provides additional information beyond symptomatic, histologic, and endoscopic assessments.
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关键词
dysphagia,eosinophilic esophagitis,stricture
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