Response to Neoadjuvant Targeted Therapy in Operable Head and Neck Cancer Confers Survival Benefit.

Marco A Mascarella,Tolani F Olonisakin,Purva Rumde,Varun Vendra,Melonie A Nance,Seungwon Kim,Mark W Kubik,Shaum S Sridharan,Robert L Ferris,Moon J Fenton,Daniel R Clayburgh,James P Ohr,Sonali C Joyce,Malabika Sen,James G Herman,Jennifer R Grandis,Dan P Zandberg,Umamaheswar Duvvuri

Clinical cancer research : an official journal of the American Association for Cancer Research（2023）

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摘要

Brief neoadjuvant therapy achieved pathologic downstaging in a subset of patients and was associated with significantly better DFS and OS as well as decreased circulating methylated SOX17 and TAC1.

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operable head,neck,cancer

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