Pharmacokinetics of dexmedetomidine in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass.
Paediatric anaesthesia(2023)
摘要
When cardiopulmonary bypass is applied, the plasma concentration of dexmedetomidine decreases due to an increase in the volume of distribution, so a loading dose is required to maintain the previous concentration.
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关键词
cardiopulmonary bypass,children,dexmedetomidine,pharmacokinetics
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