Evaluation of angiogenic apelin/apelin receptor axis in normal prostate, high grade prostatic intraepithelial neoplasia and prostatic adenocarcinoma.

H Soylu,B Unal,K Aksu,S Avci,A E Caylan,I Ustunel I

The Malaysian journal of pathology（2022）

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Abstract

Apelin and apelin receptor are increase in the process of prostate carcinogenesis. This increase may adversely affect the clinical course of prostate cancer patients by stimulating angiogenesis, which is important for invasion and metastasis in prostate cancer.

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Key words

Apelin, apelin receptor, HGPIN, prostate, cancer

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