Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer.

Jeesoo Choi,Ho Yeon Cho,Jeongseok Jeon,Kyung-A Kim,Yoon Dae Han,Joong Bae Ahn,Inbal Wortzel,David Lyden,Han Sang Kim

Frontiers in oncology（2022）

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摘要

Our findings demonstrate the feasibility of evDNA as a complementary tool to aid current methods of patient evaluation in the diagnosis and surveillance of colon cancer.

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关键词

cancer,cell-free DNA,colon cancer,ddPCR,exosomal DNA,exosome,extracellular vesicle,liquid biopsy

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