The effect of training about environmental toxicant Bisphenol-A exposure in pregnancy on maternal urine Bisphenol-A level

Purpose: Bisphenol A (BPA) is an environmental toxin, clearly capable of initiating epigenetic modifications, leading to the development of numerous human illnesses such as metabolic, reproductive, and behavioural abnormalities. It also causes oxidative stress, which has been shown to be alleviated by selenium supplementation. The purpose of this study was to determine the effect of training of BPA exposure during pregnancy on urine BPA levels. Methods: This research enrolled 30 pregnant women who were in their first trimester and were free of chronic illness. Women were asked questions on their sociodemographic features, anthropometric measures, obstetric characteristics, BPA awareness level, BPA exposure and the Health Practices in Pregnancy Scale as a Pre-test and Post-Test. The initial urine samples were taken from women in their first trimester and stored in BPA-free bags. Then, training was delivered to encourage BPA exposure reduction and maternal health awareness. First-trimester face-to- face instruction and brochure distribution were followed by refresher, reminder, and follow-up trainings during the second and third trimesters. Urine samples from women in their second and third trimesters were obtained again. The levels of BPA in urine were measured using the liquid chromatography-mass spectrometry on 90 samples. Each person's urine concentration differs, thus the creatinine level in all samples was also calculated and compared to the BPA content, and the results were evaluated. Results: Our study shown that BPA exposure may be lowered by training. It has been demonstrated that reducing BPA exposure and increasing knowledge can result in an improvement in health status. Additionally, it has been demonstrated that trainings greatly minimize exposure-causing behaviours. Conclusion: It was discovered that while the duration of a single training does not make a meaningful effect, the continuing of reminder trainings did make a substantial difference in the urine BPA level.