Growth Differentiation Factor 7 Prevents Sepsis-Induced Acute Lung Injury in Mice.

Ping Dong,Ying Zhang,Nian Liu,Jun-Yuan Yang,Hui-Min Wang,Qing Geng

Evidence-based complementary and alternative medicine : eCAM（2022）

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摘要

GDF7 prevents LPS-induced inflammatory response, oxidative stress, and ALI by regulating the STING/AMPK pathway. Our findings for the first time identify GDF7 as a potential agent for the treatment of sepsis-induced ALI.

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